No Mike Lowell. Kotsay at first. No Jed Lowrie. Cora at short.
1. CF Jacoby Ellsbury
2. 2B Dustin Pedroia
3. DH David Ortiz
4. 3B Kevin Youkilis
5. RF JD Drew
6. LF Jason Bay
7. 1B Mark Kotsay
8. C Jason Varitek
9. SS Alex Cora
SP Daisuke Matsuzaka
Cora has a decent history against Ervin Santana, 2 for 3 with a double and triple. As opposed to Lowrie, who has never faced him. Also, the 9-1-2 combination of Cora-Ellsbury-Pedroia allows for some potential small ball in a close game, if necessary.
Why Mark Kotsay instead of Sean Casey? Casey is 0 for 3 against Santana. Kotsay is 7 for 18 (.389) with two doubles.